Nifedipine & Lidocaine Cream

What Is Nifedipine & Lidocaine Cream?

Nifedipine & Lidocaine Cream is a topical prescription medicine used primarily for anorectal conditions involving pain and muscle spasm. Unlike oral nifedipine tablets used for blood pressure control, this formulation is applied locally and works at the site of application.

It is intended for external or rectal use only, as directed by a healthcare provider, and should not be used without medical advice. Unlike oral formulations such as Nifedipine Tablets 20 Mg, which are used for blood pressure management, this cream is applied locally and works at the site of application.

How Nifedipine & Lidocaine Cream Works

The pharmacological properties of nifedipine, including its calcium channel–blocking activity and effects on smooth muscle relaxation, are well documented in established medical references. For an overview of nifedipine pharmacology, refer to Nifedipine pharmacology overview.

Mechanism of Action

• Nifedipine relaxes smooth muscle by blocking calcium channels

• Helps reduce internal anal sphincter pressure

• Improves local blood flow, supporting tissue healing

• Lidocaine blocks nerve signals to provide temporary pain relief

• Reduces burning, itching, and discomfort at the application site

Therapeutic Uses

Nifedipine & Lidocaine Cream is commonly used for:

• Management of anal fissures

• Relief of pain and discomfort associated with fissures

• Reduction of anal sphincter spasm

• Supportive therapy to promote healing and comfort

Oral nifedipine products used for cardiovascular conditions are listed separately in our Blood Pressure category

Dosage and Administration

Dosage and duration of use are determined by a healthcare provider based on the patient’s condition and response to treatment.

Administration Guidelines

• Apply a small amount as prescribed

• For external or rectal use only

• Wash hands before and after application

• Do not exceed the recommended frequency

• Avoid contact with eyes or mouth

• Do not use for prolonged periods without medical advice

Side Effects

Some patients may experience side effects, although not everyone is affected.

Commonly Reported Effects

• Mild burning or irritation at the application site

• Temporary numbness

• Redness or itching

Less Common Effects

• Allergic skin reactions

• Increased irritation with prolonged use

If severe irritation, allergic reaction, or worsening symptoms occur, discontinue use and seek medical advice. Information on lidocaine and nifedipine safety profiles is consistent with established medical guidance.

Warnings and Precautions

Before using Nifedipine & Lidocaine Cream, inform your healthcare provider if you have allergies to local anesthetics, cardiovascular conditions, or are using other topical or systemic medications.

Important Safety Information

• Prescription use only

• Not intended for oral ingestion

• Avoid use on broken or infected skin unless directed

• Use during pregnancy or breastfeeding only if prescribed

• Keep out of reach of children

For further information on anal fissure treatment and when to seek medical care, refer to official guidance from the UK National Health Service (NHS).

Storage Instructions

• Store at room temperature

• Protect from heat and direct sunlight

• Keep container tightly closed

• Do not use after the expiration date

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