Description

Lapatinib Tablets 250 mg – Targeted Therapy for HER2-Positive Breast Cancer

Lapatinib Tablets 250 mg are used in the treatment of HER2-positive metastatic or advanced breast cancer, particularly in cases where cancer has progressed following prior chemotherapy or trastuzumab treatment. Lapatinib is a dual tyrosine kinase inhibitor that blocks both the epidermal growth factor receptor (EGFR or HER1) and human epidermal growth factor receptor 2 (HER2) pathways.

These growth factor receptors are involved in the uncontrolled division of cancer cells. By blocking their signaling, Lapatinib effectively reduces cancer proliferation and helps improve survival in advanced-stage breast cancer patients.

This medication is typically used in combination with capecitabine or letrozole, depending on whether chemotherapy or hormonal therapy is being used.

Key Features and Benefits

• Generic Name: Lapatinib
• Brand Equivalent: Tykerb
• Strength: 250 mg per tablet
• Drug Class: Tyrosine Kinase Inhibitor (TKI)
• Form: Oral tablets
• Prescription Status: Prescription required
• Common Combinations: Capecitabine, Letrozole
• Indications:
  • HER2-positive metastatic breast cancer
  • For patients previously treated with anthracyclines, taxanes, and trastuzumab
  • Hormone receptor-positive cancers in postmenopausal women

How Lapatinib Works

Lapatinib works by inhibiting two types of receptor tyrosine kinases: EGFR (HER1) and HER2. These receptors are often overexpressed in breast cancer cells and are responsible for signaling pathways that encourage cancer cell growth. By blocking these signals, Lapatinib interferes with the cancer cell cycle, promotes cancer cell death (apoptosis), and limits tumor escalation.

Dosage and Administration

• Standard Dose: 1,250 mg once daily (5 tablets of 250 mg), or as directed by a healthcare provider
• How to Take:
  • Take on an empty stomach (at least 1 hour before or 1 hour after a meal)
  • Swallow whole with a glass of water; do not crush or chew
• Treatment Duration: Regular intake is vital; continue as long as prescribed
• Storage: Store in a cool, dry place below 30°C. Keep away from moisture and sunlight.

Note: Dosage may vary depending on combination therapies and individual case assessments. Always follow your oncologist’s instructions.

Warnings and Precautions

• Do not use during pregnancy or while breastfeeding
• Not recommended in patients with severe liver dysfunction without medical advice
• Heart health must be monitored (risk of decreased left ventricular ejection fraction)
• Can interact with drugs like ketoconazole, clarithromycin, or rifampin
• Avoid grapefruit juice while on this medication

Regular blood work and heart monitoring may be necessary to ensure continued safety during treatment.

Common Side Effects

Lapatinib 250 mg tablets may cause side effects, some of which are common and manageable under medical supervision.

Common side effects include:

• Diarrhea
• Nausea and vomiting
• Fatigue
• Skin rash
• Decreased appetite
• Palmar-plantar erythrodysesthesia (hand-foot syndrome)

Less common but serious side effects include:

• Liver dysfunction (elevated liver enzymes)
• Heart issues (decreased heart function)
• Severe allergic reactions
• QT prolongation (heart rhythm disorder)

Report any severe or unusual symptoms to your doctor.

Why Buy Lapatinib Tablets 250 mg From Us?

• Guaranteed 100% genuine products
• Supplied by licensed and certified manufacturers
• Competitive pricing for individual and bulk purchases
• Fast and trackable worldwide shipping
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• Secure checkout system with encrypted transactions

Availability & Shipping

We ship Lapatinib Tablets 250 mg across several regions, including:

• United States
• United Kingdom
• Canada
• Australia
• UAE
• Singapore
• South Africa
• And many more

Express delivery services are available for selected countries. Kindly check shipping eligibility at checkout.

Frequently Asked Questions (FAQs)

1. What is Lapatinib 250 mg used for?

Lapatinib 250 mg is used in combination therapy to treat HER2-positive advanced or metastatic breast cancer, especially in women whose disease has progressed after previous treatments.

2. Do I need a prescription to buy Lapatinib 250 mg?

Yes, Lapatinib is a prescription-only medication and must be taken under the guidance of a qualified oncologist.

3. Can Lapatinib be used alone without any combination medication?

Lapatinib is generally more effective when used in combination with capecitabine or letrozole. Monotherapy is typically not advised unless specifically directed by a doctor.

4. What food should I avoid while taking Lapatinib?

Avoid grapefruit and grapefruit juice as it affects how the medication is metabolized in the body, increasing the risk of side effects.

5. Can Lapatinib be taken during pregnancy?

Lapatinib is not safe during pregnancy due to the risk of harm to the fetus. Effective contraceptive measures are recommended during treatment.

6. How long should I take Lapatinib?

Lapatinib treatment duration varies depending on individual response and disease progression. Some patients may be on the medication long-term.

7. What if I miss a dose?

Take the missed dose as soon as you remember on the same day. Do not double the next dose. If it’s already the next day, skip the missed dose.

8. What are the signs of Lapatinib overdose?

Overdose symptoms may include severe diarrhea, liver problems, nausea, or cardiac irregularities. Seek emergency medical help immediately.

9. Can I drink alcohol while on Lapatinib?

Alcohol is best avoided, as it can affect liver function and increase the burden on the body already managing medication-related side effects.

10. Is Lapatinib the same as Herceptin (Trastuzumab)?

No. Lapatinib is an oral tyrosine kinase inhibitor, while Herceptin (Trastuzumab) is a monoclonal antibody administered intravenously. Both target HER2 but have different mechanisms of action.

Medical Advisory Disclaimer

This product information is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your physician, oncologist, or a qualified healthcare professional before starting, stopping, or changing any medication. Never disregard medical advice or delay treatment based on this content. In case of a medical emergency, contact your local emergency services or healthcare provider immediately.