Description

Afatinib Tablets 40 mg

Overview:

Afatinib Tablets 40 mg belong to a class of drugs known as tyrosine kinase inhibitors (TKIs). Specifically developed to target and block the epidermal growth factor receptor (EGFR) found in certain types of non-small cell lung cancer (NSCLC), Afatinib helps halt cancer cell multiplication and promotes cell death.

This medication is approved as a first-line treatment for patients with EGFR mutation-positive NSCLC and is used where targeted therapy is essential for managing cancer progression.

Brand Name Variants:

• Gilotrif (Brand Name – USA)
• Xovoltib (Brand Name – EU)
• Generic Afatinib

Key Ingredients:

• Active Ingredient: Afatinib Dimaleate equivalent to Afatinib 40 mg
• Form: Oral Tablet
• Dosage: 40 mg daily or as directed by your oncologist

Indications:

Afatinib 40 mg is prescribed for:

• Non-Small Cell Lung Cancer (NSCLC), particularly in tumors with EGFR gene mutations
• Metastatic NSCLC
• Cases where prior EGFR-targeted therapies are no longer effective

Always consult a certified oncologist before using this medication.

Mechanism of Action:

Afatinib irreversibly inhibits EGFR and HER2 tyrosine kinases, which are proteins that promote the growth and spread of cancer cells. By targeting these key enzymes, Afatinib reduces tumor cell replication and may enhance apoptosis or cell death. It can be more effective than some first-generation EGFR inhibitors due to its broader and irreversible binding activity.

Dosage & Usage Instructions:

• Recommended Dose: One 40 mg tablet once per day
• Administration: Should be taken on an empty stomach (at least 1 hour before or 2 hours after eating)
• Missed Dose: Skip it if less than 12 hours remain before the next scheduled dose
• Treatment Duration: Determined by your oncology team based on your health condition and cancer progression

Dosage adjustments may be required depending on the side effects experienced by the patient.

Side Effects:

Like all targeted therapies, Afatinib may cause side effects. These could range from mild to serious and require medical attention if persistent.

Common Side Effects:

• Diarrhea
• Skin rash or acne-like eruptions
• Mouth and throat ulcers
• Loss of appetite
• Fatigue
• Dry skin

Serious Side Effects (Seek medical help immediately):

• Severe skin reactions or blisters
• Liver toxicity
• Lung inflammation (interstitial lung disease)
• Eye irritation or vision changes
• Heart rhythm disturbance

Contact your healthcare provider if any new symptoms appear or if side effects worsen over time.

Storage Information:

• Store at room temperature between 15°C to 30°C
• Keep away from direct heat, sunlight, and moisture
• Preserve in its original packaging
• Keep out of reach of children and pets

Precautions and Warnings:

• Not to be used during pregnancy due to risk of birth defects
• Breastfeeding is not recommended while on this medication
• May require liver and heart monitoring during treatment
• Inform your doctor about all current medications to avoid drug interactions
• Avoid if you have pre-existing liver or kidney disease without professional supervision

Patients of childbearing potential should use effective contraception during and after treatment as advised.

Availability & Shipping:

• Afatinib 40 mg is available in both generic and brand forms
• Ready for worldwide shipping with discreet packaging
• Orders dispatched within 24–48 hours
• Shipping options include standard and express delivery

Please check local import rules before placing an order, as regulations vary by country.

Pricing and Offers:

We provide Afatinib Tablets at competitive rates. Discounts are available for bulk purchases, NGOs, and cancer treatment programs. Payment methods include international credit cards, bank wires, UPI, and selected cryptocurrencies.

Request a custom quote and check availability by contacting our sales team.

Why Buy from Us:

• 100% Genuine and verified medication
• Sourced from GMP, WHO-certified manufacturers
• Fast, trackable delivery
• Support from licensed pharmacists
• Prescription assistance available, if required
• Best price guarantee in the oncology category
• Free medical consultation to help with cancer therapies

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• Afatinib Tablets 40 mg
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Frequently Asked Questions (FAQs)

1. What is Afatinib 40 mg used for?

Afatinib is used to treat patients with non-small cell lung cancer (NSCLC) that has specific EGFR mutations. It slows down or stops the growth of cancer cells.

2. How does Afatinib work?

Afatinib targets and blocks the EGFR and HER2 proteins in cancer cells that are responsible for excessive cell growth, helping to control tumor spread.

3. Is Afatinib a form of chemotherapy?

No, Afatinib is a targeted therapy, not a conventional chemotherapy. It works on specific genetic mutations in cancer cells, causing fewer side effects for some patients.

4. Can I eat before taking Afatinib?

No. It is best taken on an empty stomach—either 1 hour before food or 2 hours after eating—to ensure maximum absorption.

5. What should I do if I miss a dose of Afatinib?

If you miss a dose and it’s more than 12 hours before your next dose, take it as soon as possible. If less than 12 hours remain, skip the missed dose and follow your regular schedule.

6. What are common side effects of Afatinib?

Common side effects include diarrhea, rash, dry skin, and mouth ulcers. Inform your doctor if you experience persistent or severe symptoms.

7. Is Afatinib safe during pregnancy?

No. Afatinib should not be used during pregnancy as it may cause harm to an unborn baby. Effective contraception is advised during treatment and for a period after therapy ends.

8. How long should I take Afatinib?

Treatment duration depends on the patient’s response and tolerance. You should continue taking Afatinib until your doctor advises otherwise based on test results and monitoring.

9. Can Afatinib be combined with other cancer treatments?

It may be combined with other medications as part of a broader treatment strategy, depending on your diagnosis and progression. Always take combinations under medical supervision.

10. Can I buy Afatinib 40 mg online without a prescription?

We recommend that Afatinib be acquired and used only with a valid prescription. Some jurisdictions may require prescription verification before purchase or delivery.