Sofosbuvir Tablets 400 Mg – Generic Sovaldi

Description

Sofosbuvir Tablets 400 mg are a highly effective antiviral treatment for chronic Hepatitis C infection. Manufactured by various trusted pharmaceutical companies, Sofosbuvir belongs to a class of drugs known as direct-acting antivirals (DAAs). It works by inhibiting the HCV NS5B RNA-dependent RNA polymerase, an enzyme essential for the virus’s replication.

Due to its effectiveness, Sofosbuvir has become a cornerstone in Hepatitis C treatment plans. It is not used alone, but in combination with other agents such as Daclatasvir, Ledipasvir, Velpatasvir, or Ribavirin, depending on HCV genotype, liver condition, and treatment history.

Treatment duration generally ranges from 12 to 24 weeks. When used properly and in combination with other agents, cure rates can exceed 95%, even in patients with cirrhosis or those previously treated unsuccessfully.

Key Features:

• Strength: 400 mg Sofosbuvir per tablet
• Direct Acting Antiviral (DAA): Inhibits NS5B polymerase
• Used in combination therapy with other antivirals
• Suitable for multiple HCV genotypes (1–6)
• High cure rates with low relapse
• Once-daily oral dose

Dosage and Administration:

• Usual dosage: One tablet (400 mg) once daily
• To be taken with or without food
• Must be used in combination with other Hepatitis C medications
• Duration: Generally 12 or 24 weeks, depending on clinical factors
• Always follow the dosage prescribed by your healthcare provider

Precautions:

• Not to be used as monotherapy
• Not recommended during pregnancy or breastfeeding unless clearly necessary
• Should be used with caution in patients with severe kidney or liver problems
• Inform your doctor about all medications you are currently taking
• Regular monitoring may be needed (viral load, liver function tests, etc.)

Storage Instructions:

• Store below 30°C in a dry place
• Keep away from direct sunlight and moisture
• Keep out of the reach of children

FAQs – Sofosbuvir Tablets 400 mg

Q1: What is Sofosbuvir used for?
A: Sofosbuvir is used to treat chronic Hepatitis C virus infection. It must be taken in combination with other antiviral medications to be effective.

Q2: Can I take Sofosbuvir alone?
A: No. Sofosbuvir is not effective as monotherapy. It is prescribed with other drugs such as Daclatasvir, Ledipasvir, Velpatasvir, or Ribavirin depending on your genotype and treatment plan.

Q3: How does Sofosbuvir work?
A: Sofosbuvir is a nucleotide analog polymerase inhibitor that interferes with the genetic replication process of the hepatitis C virus, preventing it from multiplying.

Q4: What genotypes of Hepatitis C can be treated using Sofosbuvir?
A: Sofosbuvir is effective for all major genotypes (1 to 6) of the hepatitis C virus, depending on the combination therapy used.

Q5: For how long should I take Sofosbuvir?
A: Treatment usually lasts 12 to 24 weeks, depending on the genotype, presence of cirrhosis, and previous response to treatment. Always follow your doctor’s instructions.

Q6: What are the common side effects of Sofosbuvir?
A: Common side effects may include:

• Fatigue
• Headache
• Nausea
• Insomnia
• Anemia (particularly when combined with Ribavirin)

Report any severe or persistent side effects to a healthcare provider.

Q7: Can pregnant women take Sofosbuvir?
A: Sofosbuvir should be used in pregnancy only if clearly needed and under supervision. If combined with Ribavirin, it is strictly contraindicated during pregnancy.

Q8: Can I drink alcohol while taking Sofosbuvir?
A: Alcohol can reduce liver function and impair the effectiveness of treatment. It is strongly advised to avoid alcohol during treatment.

Q9: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose. Do not take two doses at once.

Q10: Is Sofosbuvir suitable for people co-infected with HIV?
A: Yes, Sofosbuvir can be safely used in many patients with HIV–HCV co-infection, but careful supervision is needed due to potential drug interactions.