Sirolimus Tablets 1.0 Mg

 Sirolimus Tablets 1.0 Mg

Sirolimus Tablets 1.0 Mg is an immunosuppressant medication primarily used to prevent organ rejection in patients who have undergone kidney transplantation. It belongs to the class of medicines known as mTOR inhibitors and works by suppressing specific immune responses that may cause the body to reject a transplanted organ. Sirolimus Tablets 1.0 Mg is intended for oral administration and should be used strictly under the supervision of a qualified healthcare professional.

How Sirolimus Tablets 1.0 Mg Work

Sirolimus alters immune suppression by inhibiting the mammalian target of rapamycin (mTOR), a key protein involved in cell growth and immune response. By reducing immune cell activation and proliferation, sirolimus helps lower the risk of transplant rejection while preserving graft function.

Mechanism of Action

• Inhibits mTOR signaling pathway

• Suppresses T-cell and B-cell activation

• Reduces immune-mediated organ rejection

• Helps maintain long-term transplant viability

Uses of Sirolimus Tablets 1.0 Mg

Sirolimus Tablets 1.0 Mg are used for:

Therapeutic Indications

• Prevention of kidney transplant rejection

• Long-term immunosuppressive therapy in transplant patients

• Used in combination with other immunosuppressive agents as prescribed

Sirolimus Tablets 1.0 Mg is classified under immunosuppressant and transplant medicines used in specialized clinical care.

Dosage and Administration

The dosage of Sirolimus Tablets 1.0 Mg is determined by a healthcare provider based on transplant type, blood concentration levels, and patient response.

Administration Guidelines

• Taken orally with water

• Can be taken with or without food (consistency recommended)

• Swallow tablets whole

• Do not crush, chew, or split

• Regular blood monitoring may be required

• Do not discontinue without medical advice

Side Effects of Sirolimus Tablets 1.0 Mg

Some patients may experience side effects during treatment.

Common Side Effects

• Increased cholesterol or triglyceride levels

• Mouth ulcers

• Headache

• Abdominal pain

• Diarrhea

Less Common Side Effects

• Delayed wound healing

• Increased risk of infection

• Low platelet or white blood cell count

• Liver function abnormalities

Seek immediate medical attention if severe infections, breathing difficulty, or allergic reactions occur.

Warnings and Precautions

Before using Sirolimus Tablets 1.0 Mg, inform your healthcare provider if you have liver disease, high cholesterol, infections, or a history of cancer.

Important Safety Information

• Increased risk of infections due to immune suppression

• Avoid live vaccines during treatment

• Use sun protection due to increased skin cancer risk

• Pregnancy and breastfeeding only if prescribed

• Regular laboratory monitoring is essential

Storage Instructions

• Store below 25°C

• Protect from moisture and light

• Keep out of reach of children

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