Description

Olaparib Tablets 150 Mg Online at Pinkline Exports

Olaparib 150 mg is a targeted therapy medication belonging to the class of drugs known as PARP inhibitors (Poly ADP-Ribose Polymerase inhibitors). It is commonly prescribed for treating certain types of cancers, such as ovarian, breast, pancreatic, and prostate cancers, that are linked to mutations in the BRCA1 or BRCA2 genes.

Key Uses of Olaparib 150 Mg

1. Ovarian Cancer:
   • Used as maintenance therapy in patients with recurrent ovarian cancer after a good response to platinum-based chemotherapy.
2. Breast Cancer:
   • Effective in patients with HER2-negative metastatic breast cancer with BRCA mutations.
3. Pancreatic Cancer:
   • Treats metastatic pancreatic cancer in patients with BRCA mutations.
4. Prostate Cancer:
   • Prescribed for metastatic castration-resistant prostate cancer with specific genetic mutations.

How Olaparib 150 Mg Works

Olaparib targets and inhibits the PARP enzyme, which plays a role in DNA repair. Cancer cells with defective BRCA genes rely heavily on PARP for survival. By blocking PARP, Olaparib prevents the repair of damaged DNA in cancer cells, causing them to die while sparing normal cells.

Dosage & Administration

• Recommended Dose:
  • 300 mg daily, divided into two doses of 150 mg each.
  • Should be taken with or without food, as per your doctor’s advice.
• Duration:
  • Treatment duration depends on your medical condition and response to therapy.
• Missed Dose:
  • If you miss a dose, skip it and continue with your next dose. Do not double the dose.

Benefits of Olaparib 150 Mg

1. Improves progression-free survival in cancer patients.
2. Reduces the risk of cancer recurrence.
3. Offers a targeted approach, minimizing damage to healthy cells.
4. Effective in patients with BRCA mutations.

Possible Side Effects

• Common Side Effects:
  • Nausea
  • Fatigue
  • Vomiting
  • Anemia (low red blood cell count)
  • Decreased appetite
• Serious Side Effects:
  • Bone marrow suppression
  • Risk of developing secondary cancers such as leukemia or myelodysplastic syndrome (MDS)
  • Lung inflammation (pneumonitis)
• When to Seek Medical Attention:
  • Persistent fatigue, shortness of breath, unexplained bruising, or bleeding.

Precautions

1. Pregnancy:
   • Avoid during pregnancy, as Olaparib can harm an unborn baby. Use effective contraception during treatment.
2. Breastfeeding:
   • Not recommended while taking Olaparib.
3. Kidney Function:
   • Dose adjustment may be required in patients with impaired kidney function.
4. Interactions:
   • Avoid grapefruit or grapefruit juice as it can interfere with the medication’s efficacy.
   • Inform your doctor about all medications you are taking to avoid interactions.

FAQs

1. What cancers is Olaparib used for?

• It is used to treat ovarian, breast, pancreatic, and prostate cancers, particularly in patients with BRCA mutations.

2. Can Olaparib cure cancer?

• Olaparib is not a cure but can help control cancer, slow its progression, and improve survival rates.

3. How long does it take for Olaparib to work?

• The time varies; it depends on the type and stage of cancer. Regular monitoring is necessary to assess its effectiveness.

4. Is Olaparib safe for long-term use?

• Long-term use should be evaluated by a healthcare professional based on benefits and risks, including potential side effects.

5. Can I drink alcohol while on Olaparib?

• While alcohol doesn’t directly interact with Olaparib, it may exacerbate side effects like fatigue or nausea. Limit alcohol consumption.

Storage Instructions

• Store at room temperature (20°C to 25°C).
• Keep away from moisture and direct sunlight.
• Keep out of reach of children and pets.