Mirabegron & Silodosin Capsules 50/8 Mg

Mirabegron & Silodosin Capsules 50/8 Mg is a prescription combination therapy formulated to support the management of urinary symptoms associated with benign prostatic hyperplasia (BPH) and overactive bladder (OAB) in adult patients. This product combines Mirabegron 50 mg, a β3-adrenergic receptor agonist that enhances bladder storage capacity, with Silodosin 8 mg, an α1-adrenergic blocker that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow and reduce obstruction.

How Mirabegron & Silodosin Capsules 50/8 Mg Work

Mechanism of Action

• Mirabegron activates β3-adrenergic receptors in bladder smooth muscle, increasing storage capacity and decreasing urgency and frequency of urination.

• Silodosin selectively blocks α1-adrenergic receptors in the prostate, bladder neck, and urethra, relaxing muscle tissue and improving urinary flow while reducing prostatic obstruction.

• Together, these complementary actions relieve symptoms of OAB and BPH more effectively than either agent alone in suitable patients.

Uses of Mirabegron & Silodosin Capsules 50/8 Mg

Mirabegron & Silodosin Capsules 50/8 Mg are prescribed for the management of urinary symptoms associated with benign prostatic hyperplasia and overactive bladder.
Patients and healthcare providers may explore other urology medicines for urinary symptoms to understand additional therapeutic options available for related urological conditions.

Therapeutic Indications

Mirabegron & Silodosin Capsules 50/8 Mg are prescribed for:

• Management of urinary symptoms associated with benign prostatic hyperplasia (BPH)

• Relief of overactive bladder (OAB) symptoms such as urgency, frequency, and urge incontinence

• Enhancement of urinary flow rate and reduction of incomplete bladder emptying

• Symptom control in adult men when standard monotherapy has proven insufficient

Dosage and Administration

The dosage and duration of Mirabegron & Silodosin Capsules 50/8 Mg should be individualized by a healthcare professional based on the patient’s condition and response.

Administration Guidelines

• Taken once daily with or without food

• Swallow capsules whole with water

• Do not crush, chew, or split the capsules

• Follow the prescribing clinician’s instructions strictly

Patients should refer to clinical guidelines or trusted medical references like Mirabegron extended-release tablets medical information for detailed prescribing support.

Side Effects

As with all medications, some patients may experience side effects. Consult a healthcare provider if symptoms are severe or persistent.all prescription medicines, Mirabegron & Silodosin Capsules 50/8 Mg may cause side effects in some patients.
For a detailed and patient-focused explanation of possible adverse effects, precautions, and warnings, refer to Mirabegron uses, side effects, and warnings – Drugs.com – Comprehensive drug overview.

Common Side Effects

• Dizziness or lightheadedness

• Headache

• Nasal congestion

• Abnormal ejaculation

• Urinary tract infection

• Dry mouth and gastrointestinal discomfort

Less Common Side Effects

• Orthostatic hypotension (drop in blood pressure on standing)

• Palpitations

• Constipation or diarrhea

• Fatigue

Seek medical advice if any side effect is severe or concerning.

Warnings and Precautions

Prior to use, patients should inform their healthcare provider of all medical conditions.

Important Safety Information

• Not typically indicated for women or children; intended for adult male patients.

• Caution in patients with severe liver or kidney impairment

• Avoid use if allergic to either component

• Alcohol may increase dizziness or hypotensive effects

• Not recommended for patients with uncontrolled hypotension or severe cardiovascular conditions

Storage Instructions

• Store at room temperature below 25°C

• Keep in original packaging

• Protect from moisture and direct sunlight

• Keep out of reach of children

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