Gefitinib Tablets 250 Mg – Generic Iressa

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Gefitinib Tablets 250 mg

are prescription EGFR inhibitors used as a targeted therapy for the treatment of non-small cell lung cancer (NSCLC). Gefitinib works by blocking the signals that cause cancer cells to grow and divide uncontrollably. It is typically prescribed when tumors have specific EGFR gene mutations. Administered orally once per day under a doctor’s guidance.

Description

Gefitinib Tablets 250 mg – Targeted Therapy for Non-Small Cell Lung Cancer (NSCLC)

Gefitinib Tablets 250 mg are a targeted cancer therapy belonging to a group of drugs known as epidermal growth factor receptor (EGFR) inhibitors. These medications are designed to block the signals that tumors use to grow, divide, and spread.

Gefitinib is most commonly prescribed to treat non-small cell lung cancer (NSCLC) that has EGFR gene mutations. It is typically used as a first-line treatment in adults whose cancer has spread to other parts of the body and whose tumors test positive for EGFR mutations.


Uses of Gefitinib 250 mg Tablets

Gefitinib is indicated for:

  • Non-Small Cell Lung Cancer (NSCLC) — in metastatic or advanced stages
  • Patients who have EGFR gene mutation-positive tumors
  • First-line therapy in place of or after traditional chemotherapy
  • Maintenance treatment in some cases

Your oncologist will perform tests to confirm the presence of an EGFR mutation before prescribing Gefitinib.


How Gefitinib Works

Gefitinib is a tyrosine kinase inhibitor (TKI) that specifically targets the EGFR (epidermal growth factor receptor) pathway. In certain cancers like NSCLC, the EGFR gene is mutated, resulting in uncontrolled cell division.

Gefitinib:

  • Binds to the ATP-binding site of the EGFR tyrosine kinase
  • Inhibits phosphorylation and subsequent signal transduction pathways
  • Blocks tumor growth and proliferation
  • Slows down spread (metastasis) of cancer cells
  • Induces programmed cell death (apoptosis) in cancer cells

It functions as a precision medicine, minimizing damage to surrounding healthy cells compared to conventional chemotherapy.


Gefitinib 250 mg Dosage and Administration

  • Typical Adult Dose: 250 mg tablet once daily
  • Route: Oral (by mouth)
  • Meal Consideration: Can be taken with or without food
  • Administration Tip: Take with a full glass of water at the same time daily
  • Missed Dose: Skip the missed dose if it’s almost time for your next dose. Do not double up.

Always follow your oncologist’s personalized treatment plan. Dosage may be adjusted if side effects occur or based on liver function.


Benefits of Gefitinib Therapy

  • Targets cancer cells with fewer systemic side effects
  • Shown to improve progression-free survival in EGFR-positive NSCLC
  • Oral tablet form — no hospital infusion required
  • Suitable for long-term use with routine monitoring
  • High response rate in select patient populations

Side Effects of Gefitinib Tablets

While Gefitinib is generally better tolerated than traditional chemotherapy, it may cause some adverse effects.

Common Side Effects:

  • Skin rash or acne
  • Diarrhea
  • Nail inflammation (paronychia)
  • Fatigue
  • Loss of appetite
  • Dry skin
  • Nausea and vomiting
  • Eye irritation

Serious Side Effects:

  • Interstitial lung disease (rare, but serious)
  • Liver toxicity
  • Severe diarrhea or dehydration
  • Gastrointestinal bleeding
  • Abnormal liver tests

Regular blood tests will be conducted to monitor liver function and overall health.


Precautions and Warnings

  • Not suitable for patients without EGFR mutation-positive tumors
  • Not recommended during pregnancy or breastfeeding
  • Use effective contraception during treatment and for at least 2 weeks after the last dose
  • Inform your doctor about any lung issues, liver disease, or recent infections
  • Gefitinib may impair wound healing. Inform your doctor if you are planning any surgeries
  • Ensure you’re monitored for symptoms like sudden shortness of breath or persistent cough

Drug Interactions

Gefitinib interacts with:

  • Rifampicin, carbamazepine, and other CYP3A4 inducers (may lower effectiveness)
  • Proton pump inhibitors and antacids (reduce Gefitinib absorption)
  • Warfarin (increased risk of bleeding)
  • Herbal supplements like St. John’s Wort must be avoided

Inform your healthcare provider of all prescription, over-the-counter, or herbal supplements you’re taking.


Storage Instructions

  • Store tablets below 30°C (86°F) in a cool, dry place
  • Keep in the original blister packaging until use
  • Do not store in humid or hot environments
  • Keep out of reach of children and pets
  • Dispose of unused medicine according to pharmacy guidelines

Why Order Gefitinib Tablets 250 mg From Us?

  • 100% Authentic and certified medicines
  • Sourced from reputed pharmaceutical manufacturers
  • Competitive pricing for bulk or single orders
  • Reliable and secure shipping
  • Verified prescription compliance
  • Trusted supplier of oncology medications

Frequently Asked Questions (FAQs)

1. What is Gefitinib 250 mg used for?
Gefitinib is primarily used to treat non-small cell lung cancer that has specific mutations in the EGFR gene.

2. Is Gefitinib a chemotherapy drug?
No, it is a targeted therapy known as an EGFR tyrosine kinase inhibitor.

3. How should I take Gefitinib tablets?
Take one 250 mg tablet daily, at the same time each day, with or without food.

4. Can Gefitinib be used in all lung cancer patients?
No, it is prescribed only to patients whose cancer has EGFR gene mutations confirmed through lab testing.

5. What happens if I miss a dose?
If you forget a dose and it’s close to the next scheduled dose, skip it. Do not take two doses at once.

6. Can Gefitinib be taken during pregnancy?
No, Gefitinib should not be used during pregnancy or while breastfeeding. It may harm the unborn baby.

7. Can I take antacids with Gefitinib?
It’s advised to avoid antacids and other acid-reducing agents as they may lower the absorption of Gefitinib. Consult your doctor for alternatives.

8. Are there any dietary restrictions?
There are no strict dietary restrictions, but notify your doctor about any herbal or nutritional supplements you’re using.

9. How long will I be on Gefitinib?
Treatment duration depends on your response and disease progress. Some patients continue therapy for several months to years.

10. Is a prescription required to purchase Gefitinib 250 mg?
Yes. Gefitinib is a prescription-only medication and should only be used under medical supervision.

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