Description

Fluorouracil Injection 500 mg – Chemotherapy for Multiple Cancers

Fluorouracil Injection 500 mg, also known as 5-FU, is a chemotherapeutic agent prescribed for treating various forms of cancer, including colorectal, breast, pancreatic, stomach, and skin cancer. It belongs to a class of chemotherapy agents called antimetabolites and functions as a pyrimidine analog.

By interfering with the synthesis of DNA and RNA in fast-growing cancer cells, Fluorouracil helps stop the progression of malignant tumors. It is administered intravenously under professional medical supervision in clinics, hospitals, or oncology centers.

What is Fluorouracil 500 mg Used For?

Fluorouracil Injection 500 mg is used in the treatment of:

• Colorectal Cancer (early-stage or metastatic)
• Breast Cancer
• Pancreatic Cancer
• Stomach (Gastric) Cancer
• Head and Neck Cancers
• Skin Cancer (especially basal cell carcinoma)

It is often used in combination with other oncology drugs, such as leucovorin or oxaliplatin, to improve its efficacy.

How Fluorouracil Works

Fluorouracil is an antimetabolite that mimics naturally occurring substances in the body needed for cell growth. It:

• Inhibits thymidylate synthase, blocking the production of thymidine (a DNA building block)
• Disrupts the synthesis of DNA and RNA in rapidly dividing cells
• Leads to cell cycle arrest and cell death (apoptosis) in cancer tissues

Because cancer cells divide more rapidly than normal cells, they are more sensitive to this disruption.

Administration and Dosage

Route: Intravenous (IV) or sometimes given into an artery
Usual Dosage: Varies depending on cancer type, body surface area (BSA), and protocol

Injection Types:

• Bolus Injection: Quick delivery over 1–5 minutes
• Continuous Infusion: Over several hours or days, often via infusion pump

Administered under strict oncological settings, dosage adjustments may be needed based on:

• Blood counts
• Liver and kidney function
• Side effect tolerance

Benefits of Fluorouracil Injection

• Broad-spectrum utility across different solid tumors
• Rapid action through direct bloodstream delivery
• Often used as first-line or adjuvant therapy
• Works synergistically with other drugs to improve survival rates
• Available in multiple protocols for patient-specific needs

Side Effects of Fluorouracil

Like most chemotherapy agents, Fluorouracil comes with potential side effects. They need to be monitored and managed by a healthcare professional.

Common Side Effects:

• Nausea and vomiting
• Diarrhea or mucositis (mouth sores)
• Loss of appetite
• Hair thinning or loss
• Fatigue or weakness
• Changes in skin or nail texture

More Serious Side Effects:

• Neutropenia (low white blood cells)
• Thrombocytopenia (low platelets)
• Cardiovascular complications (chest pain, heart attack in rare cases)
• Hand-foot syndrome (palmar-plantar redness, pain)
• Liver toxicity
• Severe allergic reactions

Blood tests will be regularly performed to track blood counts and organ function.

Precautions and Warnings

• Not for use during pregnancy or breastfeeding
• Use with caution in patients with pre-existing bone marrow suppression
• Monitor closely if you have cardiac history or liver/kidney impairment
• Avoid live vaccinations during chemotherapy treatment
• Hospital supervision is required for effective and safe administration
• Avoid alcohol during treatment to reduce liver strain

Drug Interactions

Fluorouracil may interact with:

• Leucovorin (enhances effectiveness)
• Warfarin (increased bleeding risk)
• Phenytoin (toxicity risk due to decreased metabolism)
• Metronidazole and other antibiotics
• Avoid concurrent use of immunosuppressive agents unless advised

Always inform your doctor about all medications, supplements, or over-the-counter products before starting therapy.

Storage Instructions

• Store vials at 15–25°C (59–77°F)
• Keep away from direct sunlight and moisture
• For hospital or oncology center use only
• Avoid freezing or shaking
• Follow local biohazard protocols for disposal

Why Buy Fluorouracil Injection 500 mg From Us?

• Sourced from GMP-certified pharmaceutical manufacturers
• Authentic, lab-tested formulation
• Competitive wholesale and retail pricing
• Temperature-controlled shipping for stability
• 24/7 customer support and logistics tracking
• Available in single vials or bulk hospital packs

Frequently Asked Questions (FAQs)

1. What is Fluorouracil Injection 500 mg used to treat?
It is used to treat various cancers including colorectal, breast, pancreatic, stomach, skin, and head & neck cancers.

2. Is Fluorouracil a form of chemotherapy?
Yes. Fluorouracil is a cytotoxic chemotherapy drug classified as an antimetabolite and pyrimidine analog.

3. How is Fluorouracil administered?
It is typically given through intravenous injection or infusion in a hospital or clinic by trained healthcare professionals.

4. How often do I receive this injection?
Your oncologist will determine the administration schedule based on your type of cancer, tolerance, and overall treatment plan.

5. Can I take Fluorouracil during pregnancy?
No. It is contraindicated during pregnancy due to risk of birth defects and fetal harm.

6. Does Fluorouracil have any serious side effects?
Yes. It can cause low white blood cell counts, liver issues, fatigue, and gastrointestinal problems. Your doctor will monitor your response with blood tests.

7. Do I need to be hospitalized to receive Fluorouracil?
In many cases, yes. Some regimens allow outpatient administration, but monitoring is always necessary.

8. Is a prescription required to buy Fluorouracil Injection?
Yes. This is a potent oncology drug that requires a valid doctor’s prescription and medical supervision.

9. Can Fluorouracil be used with other cancer treatments?
Yes. It is often combined with leucovorin, oxaliplatin, or irinotecan, depending on the cancer type and protocol.

10. How should I store unopened vials?
Store at room temperature, away from light and heat. Do not use after the expiration date or if the vial appears cloudy or discolored.