Imipramine Tablets 75 Mg – Tofranil
$21.50 – $48.00Price range: $21.50 through $48.00
Imipramine Tablets 75 mg are prescription tricyclic antidepressants used for the treatment of severe depression, anxiety disorders, and certain chronic pain conditions. This higher dose is ideal for patients who require intensive, long-term symptom control and robust mood stabilization.
Description
Imipramine Tablets 75 Mg – Tofranil
Imipramine Tablets 75 Mg – Tofranil is a tricyclic antidepressant (TCA) used to treat depression, anxiety disorders, and nocturnal enuresis (bedwetting). It helps improve mood, emotional balance, and behavioral control. This higher strength is typically prescribed for moderate to severe conditions after careful dose titration under medical supervision.
Lower strengths such asImipramine Tablets 25 Mg– Tofranil and Imipramine Tablets 50 Mg – Tofranil are used during initial therapy and dose adjustment before reaching 75 Mg for stronger symptom control.
Mechanism of Action
Neurotransmitter Reuptake Inhibition
Imipramine increases serotonin and norepinephrine levels in the brain.
Mood and Behavioral Regulation
This helps reduce depressive symptoms, control anxiety, and improve bladder regulation in children.
Medical Uses
Imipramine 75 Mg is used for:
- Depression
- Anxiety disorders
- Panic disorder
- Nocturnal enuresis (bedwetting)
Dosage and Administration
It is taken orally as prescribed, either once daily or in divided doses. This dose is generally reached after gradual titration from lower strengths to achieve optimal therapeutic response.
Clinical Effectiveness
Clinical studies show that imipramine effectively improves mood, reduces anxiety, and helps manage enuresis when used consistently under medical supervision.
Safety and Side Effects
Common Side Effects
- Dry mouth
- Drowsiness
- Constipation
- Blurred vision
Serious Risks
- Heart rhythm disturbances
- Seizures (rare)
- Severe sedation
Higher doses require close monitoring.
Contraindications and Precautions
Imipramine should be used with caution in:
- Patients with heart disease
- Individuals with glaucoma
- Patients taking MAO inhibitors
A full medical evaluation is necessary before use.
Drug Interactions
It may interact with antidepressants, sedatives, and medications affecting heart rhythm. Patients should inform their healthcare provider about all medicines they are taking.For clinical guidelines and safety information, refer to National Institute of Mental Health (NIMH) and Mayo Clinic – Imipramine Drug Information.
FAQs
Imipramine 75 Mg is used to treat depression, anxiety disorders, and nocturnal enuresis. It helps improve mood, reduce anxiety, and control bedwetting when taken regularly under medical supervision, supporting better emotional stability and daily functioning in patients with more severe symptoms requiring higher-dose therapy and long-term management for effective results.
Imipramine works by increasing serotonin and norepinephrine levels in the brain, which regulate mood and emotional balance. It also affects bladder control mechanisms, helping reduce bedwetting in children. This dual action makes it effective for treating both psychiatric conditions and certain pediatric disorders when used consistently under proper medical supervision for best outcomes.
Imipramine 75 Mg should be taken orally as prescribed by a healthcare provider, either once daily or in divided doses. It is important to follow the dosage schedule carefully and not skip doses, as consistent use ensures stable medication levels and effective symptom control for depression, anxiety, or enuresis conditions over time.
Imipramine 75 Mg can be used for long-term treatment under medical supervision, but regular monitoring is required to assess heart function and detect any adverse effects early. Patients should report symptoms such as palpitations, dizziness, or excessive drowsiness promptly to ensure continued safe and effective therapy for chronic mental health or pediatric conditions.
Common side effects include dry mouth, drowsiness, constipation, blurred vision, dizziness, and possible weight changes. These are generally mild and may improve over time as the body adjusts to the medication. Persistent or severe symptoms should be reported to a healthcare provider for evaluation and appropriate management during ongoing treatment safely.

Ella Richards –
I can now sleep properly and wake up feeling clear-headed. That’s everything for me.