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Ledipasvir 90 mg + Sofosbuvir 400 mg tablets are a combination antiviral medication used to treat chronic hepatitis C virus (HCV) infection. This fixed-dose combination targets different stages of the HCV life cycle, improving treatment efficacy and patient compliance.

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Description

Buy Ledipasvir 90 + Sofosbuvir 400 Online at Pinkline Exports

Ledipasvir 90 mg + Sofosbuvir 400 mg is a combination medication used to treat chronic hepatitis C virus (HCV) infection in adults. It belongs to the class of antiviral medications and is highly effective in eliminating the hepatitis C virus from the body, often leading to a complete cure.


Key Uses of Ledipasvir 90 + Sofosbuvir 400

  1. Chronic Hepatitis C Treatment:
    • Used for treating hepatitis C virus infections, particularly genotypes 1, 4, 5, and 6.
    • Helps prevent liver damage, cirrhosis, or liver cancer caused by the long-term presence of the hepatitis C virus.
  2. In Combination Therapy:
    • May be used with other medications, like ribavirin, for certain patients with more complex cases or advanced liver disease.

How Ledipasvir 90 + Sofosbuvir 400 Works

The combination of Ledipasvir and Sofosbuvir works synergistically to block the replication of the hepatitis C virus in the body:

  1. Ledipasvir: Inhibits a protein called NS5A, which is essential for the hepatitis C virus to replicate and assemble.
  2. Sofosbuvir: A nucleotide analog polymerase inhibitor that targets the NS5B polymerase, an enzyme necessary for viral replication.

Together, they disrupt the virus’s life cycle and prevent it from multiplying, enabling the immune system to eliminate the infection.


Dosage and Administration

  1. Standard Dose:
    • One tablet daily, taken with or without food. Follow your healthcare provider’s exact instructions.
    • Duration of therapy typically ranges from 8 to 24 weeks, depending on the severity of the infection, genotype, and patient history.
  2. Missed Dose:
    • If you miss a dose, take it as soon as you remember, unless it is close to the time for your next dose. Do not double up on doses.
  3. Important Note:
    • Do not stop taking the medication without consulting your doctor, as this may reduce its effectiveness.

Benefits of Ledipasvir 90 + Sofosbuvir 400

  1. High Cure Rates:
    • Clinical studies show a cure rate of over 90% for HCV when used as prescribed.
  2. Convenience:
    • Single-pill combination simplifies treatment and improves adherence.
  3. Fewer Side Effects:
    • Compared to older treatments like interferon-based regimens, it is well-tolerated with fewer adverse effects.
  4. Prevents Complications:
    • Reduces the risk of long-term complications such as liver failure, cirrhosis, or hepatocellular carcinoma.

Side Effects

Common Side Effects:

  • Fatigue
  • Headache
  • Nausea
  • Diarrhea
  • Insomnia

Rare but Serious Side Effects:

  • Slow heart rate (when used with amiodarone)
  • Severe allergic reactions (rash, swelling, breathing difficulty)
  • Signs of liver damage (yellowing of skin/eyes, dark urine)

If you experience any severe side effects, contact your healthcare provider immediately.


Precautions

  1. Drug Interactions:
    • Avoid using with amiodarone, as it can cause life-threatening bradycardia.
    • Antacids or medications affecting stomach acid can interfere with absorption. Take these 4 hours apart from this medication.
  2. Pregnancy and Breastfeeding:
    • Limited studies are available on its safety in pregnancy. If used with ribavirin, strict contraception is required, as ribavirin is teratogenic.
    • Discuss breastfeeding with your doctor before starting the medication.
  3. Kidney and Liver Issues:
    • Caution is advised in patients with advanced kidney disease or liver failure.
  4. Avoid Alcohol:
    • Alcohol can worsen liver damage and reduce the medication’s effectiveness.

FAQs

1. Can Ledipasvir + Sofosbuvir cure hepatitis C?

  • Yes, this combination has a very high success rate and can effectively cure hepatitis C in most cases when taken as prescribed.

2. How long will I need to take this medication?

  • Treatment duration varies depending on the severity of your infection and medical history. Typical durations are 8, 12, or 24 weeks.

3. Are there any dietary restrictions while on this medication?

  • No specific dietary restrictions are required, but avoid alcohol and high-fat meals, which may impact liver health.

4. Will hepatitis C return after treatment?

  • Once cured, hepatitis C typically does not return. However, reinfection is possible if exposed to the virus again.

5. Is monitoring necessary during treatment?

  • Yes, regular blood tests are essential to track liver function and ensure the virus is cleared from your system.

Storage

  • Store at room temperature (15°C–30°C or 59°F–86°F).
  • Keep the medication in its original container, away from moisture and light.

 

Ledipasvir 90 mg + Sofosbuvir 400 mg is a breakthrough combination therapy for treating chronic hepatitis C infections. With its high cure rates and fewer side effects, it has become a cornerstone in managing this condition. Always adhere to your doctor’s instructions, complete the full course, and attend regular follow-up appointments to ensure a successful outcome.

For bulk orders, we encourage you to contact us directly through WhatsApp, Telegram, or email. Whether you’re looking to customize your order, inquire about pricing, or discuss logistics, our dedicated team is ready to assist you every step of the way. Get in touch with us today to streamline your bulk purchasing experience and ensure your requirements are met with efficiency and reliability.

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