Ethambutol Tablets 600 Mg

What Are Ethambutol Tablets 600 mg?

Ethambutol is an antitubercular agent included in first-line treatment regimens for tuberculosis. It is considered bacteriostatic, meaning it inhibits bacterial growth rather than directly killing the bacteria. Because TB bacteria can develop resistance when single drugs are used, ethambutol is always used in combination with other TB medicines such as isoniazid, rifampicin, and pyrazinamide.

The 600 mg dose is commonly prescribed for adults based on body weight and clinical indications.

How Ethambutol Works

Ethambutol interferes with the synthesis of the mycobacterial cell wall, particularly by disrupting the formation of arabinogalactan — an essential component of the bacterial cell wall. This action weakens the bacterial structure, slows growth, and enhances the effectiveness of other antitubercular drugs in combination therapy.

This mechanism helps reduce the bacterial load in infected tissues, contributing to the control and eventual resolution of tuberculosis infection.

Indications

Ethambutol Tablets 600 mg are indicated for:

• Pulmonary tuberculosis

• Extrapulmonary tuberculosis (such as lymphatic TB)

• TB strains susceptible to first-line antitubercular therapy

• Combination therapy with isoniazid, rifampicin, and pyrazinamide

The use, dosage, and duration of treatment are determined by a clinician based on clinical presentation, TB severity, and patient characteristics.

Dosage & Administration

• Typical adult dose: 600 mg once daily

• Take with a full glass of water

• Can be taken with or without food, as advised by a doctor

• Follow your healthcare provider’s instructions exactly — do not alter the dose without professional guidance

Ethambutol should be taken as part of a complete multidrug regimen for tuberculosis to prevent drug resistance and ensure effective treatment.

Safety Information & Precautions

Before taking Ethambutol Tablets 600 mg, inform your healthcare provider if you have:

• Vision problems or eye disease

• Kidney impairment

• History of gout or elevated uric acid

• Allergies to TB medicines or other antibiotics

Vision Monitoring

A noteworthy safety consideration with ethambutol is its potential effect on the optic nerve. Patients should have baseline visual acuity and colour vision tests before starting, and regular monitoring during therapy. Report any changes in vision immediately.

Possible Side Effects

Common side effects may include:

• Vision changes (blurred vision, difficulty distinguishing colours)

• Headache

• Dizziness

• Loss of appetite

• Nausea

• Joint pain

If you experience significant vision changes, persistent headaches, or other severe symptoms, contact your healthcare provider promptly.

Drug Interactions

Ethambutol can interact with other medicines, including:

• Other antibiotics

• Antacids containing aluminum (may reduce absorption)

• Gout medications

• Other antitubercular drugs (used in combination)

Always tell your healthcare provider about all prescription and non-prescription products you use. Avoid self-medicating without professional direction.

Storage Instructions

Store Ethambutol Tablets 600 mg in a cool, dry place at temperatures below 25 °C. Protect from light and moisture. Keep out of reach of children.

FAQs