Leflunomide Tablets 10 Mg

$48.00$126.00

Leflunomide Tablets, known by the brand name Arava, are used to treat rheumatoid arthritis and other autoimmune conditions. As a disease-modifying antirheumatic drug (DMARD), Leflunomide helps to reduce inflammation and slow the progression of disease by inhibiting the growth of certain immune cells.

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Description

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Leflunomide Tablets is a medication primarily used to treat rheumatoid arthritis and other autoimmune disorders by reducing inflammation and suppressing the immune system. It contains leflunomide, which belongs to the class of drugs called disease-modifying antirheumatic drugs (DMARDs).


Uses of Leflunomide Tablets

  1. Rheumatoid Arthritis:
    • Reduces inflammation, joint pain, and stiffness.
    • Slows the progression of joint damage.
  2. Psoriatic Arthritis:
    • Helps manage symptoms like swelling, pain, and skin lesions.
  3. Other Autoimmune Disorders:
    • May be used off-label for conditions like lupus and other inflammatory diseases.

How Leflunomide Tablets Works

Leflunomide inhibits the activity of an enzyme called dihydroorotate dehydrogenase, which is necessary for the production of pyrimidines (components of DNA and RNA). This reduces the proliferation of immune cells, specifically overactive T and B lymphocytes, thereby controlling inflammation and autoimmune activity.


Dosage and Administration

  • Typical Dose:
    • Initial loading dose: 100 mg once daily for 3 days.
    • Maintenance dose: 10-20 mg once daily depending on the condition and tolerance.
  • Administration:
    • Taken orally with or without food.
    • Follow your doctor’s instructions for the best results.

Benefits of Leflunomide Tablets

  1. Effective in Controlling Symptoms:
    • Reduces pain, swelling, and stiffness in autoimmune conditions.
  2. Prevents Disease Progression:
    • Helps preserve joint function and mobility.
  3. Once-Daily Dosing:
    • Convenient for long-term management.

Precautions

  1. Pregnancy:
    • Contraindicated in pregnancy; may cause severe birth defects. Use effective contraception during and for a period after stopping treatment.
  2. Liver Function:
    • Regular liver function tests are required as leflunomide can cause liver toxicity.
  3. Infections:
    • May increase susceptibility to infections due to immune suppression.
  4. Pre-existing Conditions:
    • Inform your doctor if you have liver disease, kidney disease, or a history of tuberculosis.

Possible Side Effects

Common Side Effects:

  • Nausea or diarrhea.
  • Hair thinning or loss.
  • Increased blood pressure.
  • Rash or skin irritation.

Serious Side Effects:

  • Liver damage (jaundice, dark urine).
  • Severe infections (fever, chills).
  • Peripheral neuropathy (tingling or numbness in hands/feet).

Seek medical attention for severe or persistent side effects.


FAQs

1. How long does Leflunomide take to work?

  • It may take 4-6 weeks to notice symptom improvement, with full effects seen in 6 months.

2. Can Leflunomide be stopped abruptly?

  • No, it should not be stopped without consulting your doctor. Stopping suddenly may worsen symptoms.

3. What should I do if I miss a dose?

  • Take it as soon as you remember unless it’s almost time for the next dose. Do not double up doses.

4. Can Leflunomide be taken with other arthritis medications?

  • Yes, but only under the supervision of your doctor. It is often combined with methotrexate.

5. Does Leflunomide require monitoring?

  • Yes, regular blood tests to monitor liver function and blood cell counts are necessary.

 

Leflunomide Tablets are an effective treatment option for managing autoimmune conditions like rheumatoid arthritis. Proper use, adherence to prescribed dosages, and regular monitoring can maximize benefits and reduce risks. Always consult your healthcare provider for personalized advice.

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