Description

Imatinib Tablets 400 mg – Targeted Therapy for Cancer Treatment

Imatinib 400 mg is a powerful and targeted anti-cancer medication used to treat various types of cancer including Chronic Myeloid Leukemia (CML), Gastrointestinal Stromal Tumors (GIST), and Acute Lymphoblastic Leukemia (ALL). It belongs to the tyrosine kinase inhibitor (TKI) class of drugs and works by inhibiting abnormal proteins that cause cancerous cells to grow and multiply.

It is often prescribed as a long-term treatment and is taken orally once or twice daily, depending on the specific cancer being treated. Imatinib has revolutionized cancer treatment by offering a targeted approach with fewer side effects compared to traditional chemotherapy.

Key Features and Benefits

• Generic Name: Imatinib Mesylate
• Strength: 400 mg per tablet
• Dosage Form: Oral tablet
• Therapeutic Class: Tyrosine Kinase Inhibitor
• Prescription Required: Yes
• Typical Pack Size: 30 or 60 tablets
• Manufactured under: WHO-GMP certified facilities

Indications

Imatinib 400 mg is commonly prescribed for the treatment of:

• Chronic Myeloid Leukemia (CML) in chronic, accelerated, or blast phase
• Gastrointestinal Stromal Tumors (GIST)
• Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)
• Dermatofibrosarcoma Protuberans (DFSP)
• Systemic Mastocytosis and Hypereosinophilic Syndrome

How It Works

Imatinib works by blocking the activity of specific enzymes, particularly BCR-ABL tyrosine kinase, which is produced by cancer cells in CML and ALL. This action prevents the growth and survival of abnormal cancer cells while sparing healthy cells, thus reducing side effects.

It also inhibits c-KIT and PDGF receptors, which play a role in GIST and other tumors. By targeting these specific pathways, Imatinib slows or stops the progression of cancer.

Dosage and Administration

• Standard Dosage:
  • CML: 400–600 mg once daily, can vary based on disease phase
  • GIST: Often starts at 400 mg once daily, can be increased to 600 or 800 mg
• Method: Oral administration with a full glass of water
• Intake: Take with food to help reduce nausea or stomach upset
• Missed Dose: Skip the missed dose if close to the next scheduled dose
• Overdose: Seek immediate medical attention
• Storage: Keep in a dry place, below 30°C, and out of reach of children

Always follow the dosage prescribed by your treating physician.

Warnings and Precautions

• Not recommended for use in pregnant or breastfeeding women
• Regular blood tests are needed to monitor liver function and blood counts
• May interact with certain antibiotics, antifungals, and seizure medications
• Avoid grapefruit juice and supplements containing St. John’s Wort
• Caution is advised in patients with heart, liver, or kidney impairment

Common Side Effects

While Imatinib is generally well-tolerated, some individuals may experience side effects. Report any unusual or persistent symptoms to your doctor.

Common side effects include:

• Nausea and vomiting
• Diarrhea
• Muscle cramps or joint pain
• Fatigue
• Skin rash
• Edema (fluid retention)

Severe side effects may include:

• Liver toxicity
• Decreased blood cell counts (anemia, neutropenia, thrombocytopenia)
• Heart rhythm disturbances
• Serious allergic reactions

Medical follow-ups are necessary during treatment to monitor your response and manage side effects.

Why Choose Us to Buy Imatinib 400 mg Tablets?

• Guaranteed genuine and high-quality medications
• Supplied directly from licensed manufacturers
• Competitive prices and bulk order discounts
• Fast and reliable international delivery
• Secure checkout and sitemap-optimized for easy shopping
• Friendly support team and order tracking

Shipping and Availability

We ship Imatinib Tablets 400 mg to a wide range of locations across USA, UK, Australia, UAE, Singapore, Canada, South Africa, and more. Delivery time depends on your location and chosen shipping method.

Frequently Asked Questions (FAQs)

1. What is Imatinib 400 mg used for?

Imatinib 400 mg is used to treat Chronic Myeloid Leukemia (CML), Gastrointestinal Stromal Tumors (GIST), and Acute Lymphoblastic Leukemia (ALL), among other cancers.

2. Is a prescription required to buy Imatinib 400 mg?

Yes, Imatinib is a prescription-only medication. A registered healthcare provider must approve its use.

3. Can I take Imatinib 400 mg with other medications?

Possibly. However, Imatinib can interact with other medications. Always inform your doctor of all drugs, supplements, and over-the-counter medications you are taking.

4. Does Imatinib cure cancer?

Imatinib is not a cure but a treatment that controls and manages certain types of cancers. Many patients experience long-term remission with proper adherence.

5. How long do I need to take Imatinib?

Treatment duration depends on the type and severity of your cancer. Some patients may need to take Imatinib for several years or even lifelong.

6. Can Imatinib cause hair loss?

Hair loss is rare with Imatinib but may occur in some patients. Side effects vary from person to person.

7. What should I do in case of an overdose?

Seek immediate emergency medical care. Symptoms may include nausea, vomiting, swelling, low blood pressure, or irregular heart rate.

8. Can pregnant women take Imatinib?

No. Imatinib is not recommended during pregnancy due to potential harm to the unborn baby. Women of childbearing age should use effective contraception.

9. What are the signs of serious side effects?

Unexplained bruising, persistent stomach pain, dark-colored urine, yellowing of the skin, or trouble breathing should be reported to a doctor immediately.

10. How should Imatinib be stored?

Store it at room temperature, away from heat and moisture. Keep out of reach of children and pets.